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Equine GH: Growth, Performance, Ethics

Equine GH (eGH) has been available since 1998 as an approved drug (EquiGen-5, Bresagen) containing recombinant eGH (reGH). Unveiling the Power of Equine Growth Hormone : From Pastures to Performance

In the world of equine health and performance, there exists a fascinating yet lesser-known player – Equine Growth Hormone (GH). Just as growth hormone plays a pivotal role in human development, equine growth hormone governs the growth, development, and overall health of horses. This blog post delves into the intriguing world of equine growth hormone, its functions, applications, and the ethical considerations surrounding its use.

Understanding Equine Growth Hormone

Equine Growth Hormone (GH), also known as somatotropin, is a peptide hormone produced and secreted by the pituitary gland in horses. This hormone plays a crucial role in various physiological processes, including growth, metabolism, and maintenance of body composition. GH stimulates the production of Insulin-like Growth Factor 1 (IGF-1), which in turn promotes cell growth and division throughout the body.

Functions of Equine Growth Hormone

  1. Growth and Development: During a horse’s early years, GH is responsible for promoting skeletal and muscular growth, contributing to the horse’s overall size and strength.
  2. Metabolism: GH aids in regulating energy metabolism by influencing the breakdown of fats and carbohydrates. It helps maintain a healthy body composition and muscle-to-fat ratio.
  3. Muscle Development: Equine athletes rely heavily on well-developed muscles for optimal performance. GH supports the growth and maintenance of lean muscle mass, contributing to a horse’s athletic abilities.
  4. Bone Health: GH plays a role in bone growth and mineralization, ensuring strong and healthy bones that can withstand the demands placed on them during various activities.
  5. Immune System: GH influences the immune system’s function, contributing to a horse’s ability to fight off infections and diseases.

Applications of Equine Growth Hormone

  1. Sport Horses: In the competitive world of equine sports, GH has been explored for its potential to enhance muscle development, improve performance, and aid in recovery. However, its use in this context is subject to strict regulations and ethical considerations.
  2. Recovery from Injury: GH may play a role in facilitating the recovery process after injuries by promoting tissue repair and regeneration.
  3. Aging Horses: As horses age, their GH production may decrease. Some studies suggest that supplementing older horses with GH could help maintain muscle mass, bone density, and overall vitality.

Ethical Considerations

The use of equine growth hormone is a subject of ethical debate within the equine industry. The desire to enhance performance and achieve competitive advantages must be balanced with the health and welfare of the animals. Unregulated use of GH could potentially lead to health risks and unintended consequences.

Furthermore, the long-term effects of GH supplementation in horses are not fully understood, and more research is needed to determine the optimal dosages, protocols, and potential risks associated with its use.


Equine Growth Hormone is an intriguing and multifaceted hormone that plays a crucial role in the growth, development, and overall health of horses. While its potential applications in enhancing athletic performance and aiding recovery are exciting, responsible and ethical use is paramount to ensure the well-being of the animals. As our understanding of equine growth hormone continues to evolve, it’s essential to strike a balance between advancements in science and the ethical treatment of these magnificent creatures that have been our partners for centuries.