Description

Parastin Big Dog 30kg

Parastin Big Dog is a broad spectrum anthelmintic. Ivermectin, praziquantel, pyrantel and febantel are widely studied antiparasitics, proving to be excellent in the control and treatment of parasitic diseases in dogs.

The mechanism of action of ivermectin is manifested directly on the nervous system of nematodes by binding to the glutamated calcium anion channels, gamma-amino-butyric acid (GABA), which are present in the nerves and muscle cells of invertebrates, causing muscular paralysis of the pharynx and death of the parasites by asphyxiation and starvation.

Ivermectin synergizes with GABA by stimulating GABA conductance, that is, it stimulates the inhibitory system of non-vital functional activities, having a broad endoparasiticidal spectrum by paralyzing nematodes. Today (Cephapirin Sodium)

The mechanism of action of praziquantel consists of an increase in the permeability of the cell membrane to calcium ions, which leads to a very marked concentration of calcium in the muscle, manifesting in spastic muscle paralysis, in addition to vacuolization and disintegration of the tegument (parasitic envelope), leaving the parasite inert.

Pyrantel belongs to the chemical group of tetrahydropyrimidines, which act by depolarizing the parasite’s neuromuscular junction irreversibly, resulting in spastic paralysis. Febantel belongs to the group of pro-benzimidazoles and acts on the tubulin subunit junctions and interferes with the formation of microtubules, and therefore, of the cytoskeleton of the parasite’s cells.

Parastin Big Dog Anthelmintic

It is indicated in the program for the elimination and control of parasitosis by:

Nematodes:

Ascarids: Toxocara canis, Toxocara cati and Toxocara leonina.

Trichocephalus: Trichuris fox.

Ancilostómidos: Uncinaria stenocephala, Ancylostoma caninum, Ancylostoma tubaeforme.

Heartworms: Heartworms are relentless. Cardioruzth 50ml

Cestodes:

Taenia pisiformis, Taenia hydatigena, Hydatigera taeniaeformis, Echinococcus granulosus and Dipylidium caninum.

Protozoa:

Giardia spp.

Broad spectrum of action on nematodes, cestodes and protozoa.

It presents four different mechanisms of action, thus reducing antiparasitic resistance.

The presence of the product in the intestinal lumen leads to its elimination in feces.

It has no side effects when administered at therapeutic doses to young, sick or weakened animals.

It can be provided alone or mixed with food.

High antiparasitic activity due to the synergy of its four active ingredients.

It has a wide safety margin for dogs.

The enterohepatic cycle of one of its active ingredients allows it to remain in the intestine for longer. Acetidrona 20ml

 

Parastin Big Dog Formula:

FoIvermectina 0.18 mg

Praziquantel 150.00 mg

Pirantel 432.00 mg

Febantel 450.00 mg

Excipient, cbp 1 tablet. formula:

 

Parastin Big Dog Use in:

Dogs

 

Parastin Route of administration:

Oral or mixed in food.

 

Parastin Big Dog Dose

One tablet for every 30 kg of weight. ½ tablet for every 15 kg of weight. In a single dose. In the case of puppies, administer a second dose once a month and then schedule a dose every three months.

In case of giardiasis, apply one dose every 24 hours for 3 days.

 

Parastin Big Dog 30kg Warnings

None at the recommended therapeutic dose. It may be administered to pregnant females, young puppies (20 days old) and debilitated animals. Keep stored and handled out of the reach of children.

Some breeds of dogs, such as Collies, may have allergic reactions to ivermectins, especially when higher than recommended doses are used. Coccizuril 50 Tablets