Equidone Gel


Equidone Oral Gel (domperidone) for horses is prescribed by veterinarians to treat and help prevent fescue toxicosis, a disorder caused by an endophytic fungus which infects tall fescue grass. Equidone Gel is FDA-approved to help prevent fescue toxicosis and can provide less stress for you during foaling and rebreeding.


For prevention of fescue toxicosis, a warm season condition characterized by reduced feed intake and weight gains or milk production, in periparturient mares.

Possible Side Effects

The most common adverse reactions associated with treatment with Equidone Gel are premature lactation (dripping of milk prior to foaling) and failure of passive transfer.

Drug & Food Interactions

Horses with hypersensitivity to domperidone should not receive Equidone Gel.


Equidone Gel may lead to premature birth, low birth weight foals or foal morbidity if administered > 15 days prior to the expected foaling date. Accurate breeding date(s) and an expected foaling date are needed for the safe use of Equidone Gel. The safety of Equidone Gel has not been evaluated in breeding, pregnant and lactating mares other than in the last 45 days of pregnancy and the first 15 days of lactation.

The safety in stallions has not been evaluated. The long term effects on foals born to mares treated with Equidone Gel have not been evaluated. Do not use in horses with suspected or confirmed gastrointestinal blockage. Use of Equidone Gel may cause a false positive on the milk calcium test used to predict foaling.


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